EphB1 Recombinant Rabbit Monoclonal Antibody (022), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
EphB1
Concentration
1 mg/mL
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
9330129L11; AW488255; C130099E04Rik; Cek6; EK6; ELK; Elkh; ELK-related protein tyrosine kinase; ENSMUSG00000074119; Eph receptor B1; Eph receptor B2 (ELK-related protein tyrosine kinase); eph tyrosine kinase 2; EPHB1; Ephb2; EPH-like kinase 6; Ephrin type-B receptor 1; EPHT2; Epth2; Erk; Hek6; NET; Neuronally-expressed EPH-related tyrosine kinase; soluble EPHB1 variant 1; tyrosine-protein kinase receptor EPH-2
Gene Symbols
EPHB1
Isotype
IgG
Purification Method
Protein A
Product Type
Antibody
Clone
022
Applications
ELISA
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P54762
Gene ID (Entrez)
2047
Immunogen
Recombinant Human EphB1 protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
EPHB1
Related Products
Description
- Specificity: Human EphB1 EPHB1 is a receptor tyrosine kinase that belongs to the ephrin receptor family
- Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation
- EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain
- ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals
- ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues
- Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly
- Members of this protein family are implicated in neuronal and vascular cell targeting.