TrkC Monoclonal Antibody (08), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
TrkC
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C
Gene Symbols
Ntrk3
Isotype
IgG1
Purification Method
Protein A
Product Type
Antibody
Clone
08
Applications
ELISA
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q16288
Gene ID (Entrez)
4916
Immunogen
Recombinant Human TrkC/NTRK3 Protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
Ntrk3
Related Products
Description
- Specificity: Human TrkC/NTRK3 NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
- Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1
- The different isoforms do not have identical signaling properties
- The protein is widely expressed, mainly in the nervous tissue
- The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain
- TRKC is subject to ligand-mediated auto-phosphorylation
- The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.