7240453
ADSL Recombinant Rabbit Monoclonal Antibody (001), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
ADSL
Concentration
1 mg/mL
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
2510006M18Rik; Adenylosuccinase; adenylosuccinate lyase; adenylosuccinate lyase 1; Adl; Adsl; AMPS; argininosuccinase; argininosuccinate lyase; Arginosuccinase; ASAL; ASase; ASL; null; test; unnamed protein product
Gene Symbols
Adsl
Isotype
IgG
Purification Method
Protein A
Product Type
Antibody
Clone
001
Applications
ELISA
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P30566
Gene ID (Entrez)
158
Immunogen
Recombinant Human ADSL/Adenylosuccinate Lyase protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
Adsl
Related Products
Description
- Specificity: Human ADSL/Adenylosuccinate Lyase ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate
- Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP
- Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting
- Multiple isoforms of ADSL exist due to alternative splicing events.