7240519

CD275 (B7-H2) Monoclonal Antibody (05), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD275 (B7-H2)

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

AU044799; B7 homolog 2; B7 homologue 2; B7h; B7H2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP1; B7RP-1; BG071784; CD275; GI50; GL50; GL50-B; ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell costimulator ligand; inducible T-cell co-stimulator ligand; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791; transmembrane protein B7-H2 ICOS ligand

Gene Symbols

ICOSLG

Isotype

IgG1

Purification Method

Protein A

Product Type

Antibody

Clone

05

Applications

ELISA

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

O75144

Gene ID (Entrez)

23308

Immunogen

Recombinant Human ICOSL/ICOS ligand/B7-h2 Protein.

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

ICOSLG

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Description

  • Specificity: Human ICOSL/ICOS ligand/B7-h2 Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS)
  • ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function
  • ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue
  • Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.