IL12RB1 Monoclonal Antibody (05), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IL12RB1
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
CD212; cluster of differentiation 212; IL-12 receptor beta component; IL-12 receptor subunit beta-1; IL12R; IL-12R subunit beta-1; IL-12R[b]; IL12RB; Il12rb1; IL-12RB1; IL-12R-BETA1; IL-12R-beta-1; IMD30; interleukin 12 receptor subunit beta 1; interleukin 12 receptor, beta 1; interleukin-12 receptor beta-1 chain; Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component); interleukin-12 receptor subunit beta-1; MGC34454
Gene Symbols
IL12RB1
Isotype
IgG2b
Purification Method
Protein A
Product Type
Antibody
Clone
05
Applications
ELISA
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P42701
Gene ID (Entrez)
3594
Immunogen
Recombinant Human IL12RB1 Protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
IL12RB1
Related Products
Description
- Specificity: Human IL12RB1 The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily
- This protein binds to interleukin 12 with a low affinity, and is thought to be a part of IL12 receptor complex
- This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity
- The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling
- The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections
- Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.