GP130 Recombinant Rabbit Monoclonal Antibody (230), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
GP130
Concentration
1 mg/mL
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
5133400A03Rik; AA389424; Ac1055; BB405851; CD130; CD130 antigen; CDW130; D13Ertd699e; EGK_16499; Gp130; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6RB; IL-6R-beta; IL6R-beta; IL6ST; interleukin 6 signal transducer; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin 6 signal transducer receptor; interleukin receptor beta chain; interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; interleukin-6 signal transducer receptor; membrane glycoprotein; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha
Gene Symbols
IL6ST
Isotype
IgG
Purification Method
Protein A
Product Type
Antibody
Clone
230
Applications
ELISA
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Mouse
Gene Accession No.
Q00560
Gene ID (Entrez)
16195
Immunogen
Recombinant Mouse gp130/CD130/IL6ST protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
IL6ST
Related Products
Description
- Specificity: Mouse gp130/CD130/IL6ST The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM)
- This protein functions as a part of the cytokine receptor complex
- The activation of this protein is dependent upon the binding of cytokines to their receptors
- vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein
- Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis
- Alternatively spliced transcript variants encoding distinct isoforms have been described.