7240834

SRY Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SRY

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q05066

Gene ID (Entrez)

6736

Immunogen

Met1-Leu204 (Accession Q05066), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

SRY

Concentration

0.55 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

essential protein for sex determination in human males; HMG box transcription factor Sry1; HMG box transcription factor Sry3BI; sex determining region of Chr Y; sex determining region on Y; sex determining region Y; sex determining region Y protein; sex-determining region on Y; sex-determining region Y protein; SRXX1; SRXY1; Sry; Sry1; Sry3BI; SRYGENE; TDF; TDY; Testis determining locus; testis determining-Y; testis-determining factor; testis-determining factor on Y

Gene Symbols

SRY

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins
  • This protein is the testis-determining factor (TDF), which initiates male sex determination
  • Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.