7240855
Aquaporin 4 Monoclonal Antibody (C9), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Aquaporin 4
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
Aqp4; AQP-4; aquaporin 4; aquaporin type4; Aquaporin4; aquaporin-4; HMIWC2; Mercurial-insensitive water channel; MGC22454; MIWC; MIWC2; WCH4
Gene Symbols
AQP4
Isotype
IgG2a κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
C9
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P55087
Gene ID (Entrez)
361
Immunogen
Cys178-Gly317 (Accession P55087), with N-terminal His and GST Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
AQP4
Related Products
Description
- In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers
- Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane
- This function is conserved in animals, plants and bacteria
- Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10
- Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell
- Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.