7240802
Adrenomedullin Monoclonal Antibody (C1), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Adrenomedullin
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
ADM; Adrenomedullin; AM; AMpreproadrenomedullin; Ap; H39316; PAMP; preproadrenomedullin; proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide; ProAM-N20; RATAP
Gene Symbols
ADM
Isotype
IgG1 κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
C1
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P35318
Gene ID (Entrez)
133
Immunogen
Ala22-Gly147 (Accession P35318), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
ADM
Related Products
Description
- Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity
- ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning
- In hypertensive patients, the level of ADM in plasma is upregulated
- Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage
- ADM has strong natriuretic actions
- ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption
- ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.