7240911
Chemerin Monoclonal Antibody (E10), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Chemerin
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
0610007L05Rik; AI303516; Chemerin; HP10433; Rarres2; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; retinoic acid receptor responder 2; retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG2; TIG-2; TIG2HP10433
Gene Symbols
Rarres2
Isotype
IgG2b κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
E10
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q99969
Gene ID (Entrez)
5919
Immunogen
Ala33-Lys158 (Accession Q99969), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
Rarres2
Related Products
Description
- Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs)
- Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted
- TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine
- TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids
- TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells
- TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.