7240927
SGPL1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
SGPL1
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O95470
Gene ID (Entrez)
8879
Immunogen
Gln239-Arg493 (Accession O95470), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
SGPL1
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
AI428538; D10Xrf456; FLJ13811; hSPL; KIAA1252; mSPL; S1PL; Sgpl1; Spgl1; sphingosine phosphate lyase 1; sphingosine-1-phosphate aldolase; Sphingosine-1-phosphate lyase 1; sphingosine-1-phosphate lyase 1-like protein; spl; SPL 1; SP-lyase 1; zgc:162153
Gene Symbols
SGPL1
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1 phosphate, into fatty aldehydes and phosphoethanolamine
- Elevates stress-induced ceramide production and apoptosis
- The catalytic activity of sphingosine 1- phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor
- Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum
- Sphingosine 1-phosphate lyase is found primarily in the liver and kidney
- Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family.