7241010

PLAA Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PLAA

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q9Y263

Gene ID (Entrez)

9373

Immunogen

Glu162-Ala312 (Accession Q9Y263), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

Plaa

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

2410007N06; AI536418; AU018445; AW208417; D4Ertd618e; DOA1; DOA1 homolog; phospholipase A2 activating protein; phospholipase A2, activating protein; phospholipase A-2-activating protein; phospholipase A2-activating protein; PLA2P; Plaa; PLAP; Ufd3

Gene Symbols

Plaa

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • Phospholipase A-2-activating protein (PLAA), also named PLAP, can interact with ubiquitin and is involved in the maintenance of ubiquitin levels
  • PLAA contains multiple consensus domains including WD repeats, PFU domain and PUL domain
  • Although the function of PLAA remains unclear, ubiquitin binding of PLAA might be the central role that connects ubiquitination and degradation in ERAD
  • Recent finding revealed that PLAA served as a novel nociceptive mediator after incision, and its expression level is regulated by miR-203.