7245383

IGFBP-1 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IGFBP-1

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P08833

Gene ID (Entrez)

3484

Immunogen

E.coli-derived Recombinant Human IGF-BP1

Purification Method

Antigen affinity chromatography

Gene

IGFBP1

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

AFBP; alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP 1; hIGFBP1; hIGFBP-1; IBP 1; IBP1; IBP-1; IGF BP25; IGFBA; IGF-binding protein 1; IGFBP; IGFBP 1; Igfbp1; Igfbp-1; IGF-BP25; Insulin like growth factor binding protein; insulin like growth factor binding protein 1; insulin-like growth factor binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12

Gene Symbols

IGFBP1

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-BP1
  • Anti-Human IGF-BP1-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect hIGF-BP1 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IGF-BP1 (500-P228) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hIGF-BP1
  • Western Blot: To detect hIGF-BP1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant hIGF-BP1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P228BT-1MG will be provided as 2 x 500 μg This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain
  • The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma
  • Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.