IGFBP7 Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
IGFBP7
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q16270
Gene ID (Entrez)
3490
Immunogen
E.coli-derived Recombinant Human IGF-BP7
Purification Method
Antigen affinity chromatography
Gene
IGFBP7
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
Gene Symbols
IGFBP7
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-BP7
- Anti-Human IGF-BP7-specific antibody was purified by affinity chromatography employing an immobilized Human IGF-BP7 matrix
- Sandwich ELISA: To detect Human IGF-BP7 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human IGF-BP7 (500-P234Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IGF-BP7
- Western Blot: To detect Human IGF-BP7 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human IGF-BP7 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family
- IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors
- This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs
- It also stimulates prostacyclin production and cell adhesion
- Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.