89-005-658

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-005-658-Each-of-1 In Stock ₹ 44,411.00

89-005-658 - Each of 1

₹ 44,411.00

In Stock

Quantity

1

Base Price: ₹ 44,411.00

GST (18%): ₹ 7,993.98

Total Price: ₹ 52,404.98

Antigen

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length human ITGAV protein.

Gene

ITGAV

Gene Alias

CD51/DKFZp686A08142/MSK8/VNRA

Host Species

Mouse

Quantity

50 μL

Whole Molecule

Yes

Gene ID (Entrez)

3685

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications

Western Blot

Conjugate

Unconjugated

Formulation

No additive

Gene Accession No.

NM_002210

Gene Symbols

ITGAV

Immunogen

ITGAV (NP_002201, 1 a.a. ∼ 1048 a.a) full-length human protein.

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Serum

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Description

  • ITAGV encodes integrin alpha chain V
  • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
  • The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins
  • Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR)
  • In addition to adhesion, many integrins are known to facilitate signal transduction
  • Alternative splicing results in multiple transcript variants
  • [provided by RefSeq] Sequence: MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSQMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET