89-016-472

CCND2, Mouse, Clone: 3B10, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-016-472-Each-of-1 In Stock ₹ 46,458.00

89-016-472 - Each of 1

₹ 46,458.00

In Stock

Quantity

1

Base Price: ₹ 46,458.00

GST (18%): ₹ 8,362.44

Total Price: ₹ 54,820.44

Antigen

CCND2

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC010958

Gene Symbols

CCND2

Immunogen

CCND2 (AAH10958, 190 a.a. ∼ 289 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA, Western Blot

Clone

3B10

Description

Mouse monoclonal antibody raised against a partial recombinant CCND2.

Gene

CCND2

Gene Alias

KIAK0002/MGC102758

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

894

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Liquid

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Description

  • The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle
  • Cyclins function as regulators of CDK kinases
  • Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event
  • This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition
  • This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb
  • Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation
  • High level expression of this gene was observed in ovarian and testicular tumors
  • [provided by RefSeq Sequence: TDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL