89-021-024

CDK4, Mouse, Clone: 8C3, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-021-024-Each-of-1 In Stock ₹ 42,898.00

89-021-024 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

CDK4

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC003644

Gene Symbols

CDK4

Immunogen

CDK4 (AAH03644, 211 a.a. ∼ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA, Western Blot

Clone

8C3

Description

Mouse monoclonal antibody raised against a partial recombinant CDK4.

Gene

CDK4

Gene Alias

CMM3/MGC14458/PSK-J3

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1019

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Liquid

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Description

  • The protein encoded by this gene is a member of the Ser/Thr protein kinase family
  • This protein is highly similar to the gene products of S
  • cerevisiae cdc28 and S
  • pombe cdc2
  • It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression
  • The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a)
  • This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb)
  • Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers
  • Multiple polyadenylation sites of this gene have been reported
  • [provided by RefSeq Sequence: KPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE