89-018-386
mitogen-activated protein kinase kinase 2, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-018-386-Each-of-1 | In Stock | ₹ 49,662.00 |
89-018-386 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,662.00
GST (18%): ₹ 8,939.16
Total Price: ₹ 58,601.16
Antigen
mitogen-activated protein kinase kinase 2
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against a full-length human MAP2K2 protein.
Gene
MAP2K2
Gene Alias
FLJ26075/MAPKK2/MEK2/MKK2/PRKMK2
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
Immunofluorescence, Western Blot
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_030662
Gene Symbols
MAP2K2
Immunogen
MAP2K2 (NP_109587.1, 1 a.a. ∼ 400 a.a) full-length human protein.
Quantity
100 μg
Research Discipline
Kinases
Gene ID (Entrez)
5605
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG
Related Products
Description
- The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family
- This kinase is known to play a critical role in mitogen growth factor signal transduction
- It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3
- The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases
- Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome
- The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax
- A pseudogene, which is located on chromosome 7, has been identified for this gene
- [provided by RefSeq Sequence: MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV