89-018-387
mitogen-activated protein kinase kinase 3, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-018-387-Each-of-1 | In Stock | ₹ 49,662.00 |
89-018-387 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,662.00
GST (18%): ₹ 8,939.16
Total Price: ₹ 58,601.16
Antigen
mitogen-activated protein kinase kinase 3
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against a full-length human MAP2K3 protein.
Gene
MAP2K3
Gene Alias
MAPKK3/MEK3/MKK3/PRKMK3
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
In situ PLA, Western Blot
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_145109.1
Gene Symbols
MAP2K3
Immunogen
MAP2K3 (NP_659731.1, 1 a.a. ∼ 347 a.a) full-length human protein.
Quantity
100 μg
Research Discipline
Kinases
Gene ID (Entrez)
5606
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG
Related Products
Description
- The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family
- This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade
- It phosphorylates and thus activates MAPK14/p38-MAPK
- This kinase can be activated by insulin, and is necessary for the expression of glucose transporter
- Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells
- The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis
- Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene
- [provided by RefSeq Sequence: MESPASSQPASMPQSKGKSKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS