89-018-813
dual specificity phosphatase 1, Mouse, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-018-813-Each-of-1 | In Stock | ₹ 30,794.00 |
89-018-813 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,794.00
GST (18%): ₹ 5,542.92
Total Price: ₹ 36,336.92
Antigen
dual specificity phosphatase 1
Classification
Polyclonal
Description
Mouse polyclonal antibody raised against a partial recombinant DUSP1.
Gene
DUSP1
Gene Alias
CL100/HVH1/MKP-1/MKP1/PTPN10
Host Species
Mouse
Quantity
50 μL
Research Discipline
Cell Cycle
Gene ID (Entrez)
1843
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Formulation
50% glycerol
Gene Accession No.
NM_004417
Gene Symbols
DUSP1
Immunogen
DUSP1 (NP_004408, 305 a.a. ∼ 367 a.a) partial recombinant protein with GST tag.
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Serum
Related Products
Description
- The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors
- It specifies a protein with structural features similar to members of the nonreceptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus
- The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues
- Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes
- Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation
- [provided by RefSeq Sequence: LLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC