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89-109-394

HLA-G and B2M, Mouse, Clone: 87G, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-109-394-Each-of-1 In Stock ₹ 53,133.00

89-109-394 - Each of 1

₹ 53,133.00

In Stock

Quantity

1

Base Price: ₹ 53,133.00

GST (18%): ₹ 9,563.94

Total Price: ₹ 62,696.94

Antigen

HLA-G and B2M

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

ELISA (1 ug/mL) Flow Cytometry (2 ug/ml) Immunohistochemistry (Frozen sections) (10 ug/mL) The optimal working dilution should be determined by the end user.

Gene

HLA-G

Gene Symbols

HLA-G

Immunogen

HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1and HLA-G5). HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells. This antibody blocks interaction of HLA-G with inhibitory receptors.

Content And Storage

Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Frozen)

Clone

87G

Description

Mouse monoclonal antibody raised against HLA-G and B2M.

Formulation

In PBS, pH 7.4

Gene Alias

MHC-G

Host Species

Mouse

Purification Method

Protein-A affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3135

Target Species

Human

Form

Liquid

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Description

  • HLA-G belongs to the HLA class I heavy chain paralogues
  • This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
  • The heavy chain is anchored in the membrane
  • HLA-G is expressed on fetal derived placental cells
  • The heavy chain is approximately 45kDa and its gene contains 8 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail
  • [provided by RefSeq