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89-111-855

HLA-G, Mouse, FITC, Clone: 2A12, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-111-855-Each-of-1 In Stock ₹ 88,911.00

89-111-855 - Each of 1

₹ 88,911.00

In Stock

Quantity

1

Base Price: ₹ 88,911.00

GST (18%): ₹ 16,003.98

Total Price: ₹ 1,04,914.98

Antigen

HLA-G

Classification

Monoclonal

Concentration

1 mg/mL

Description

Mouse monoclonal antibody raised against synthetic peptide HLA-G.

Formulation

In PBS, pH 7.4 (0.09% sodium azide)

Gene Alias

MHC-G

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody allows to discriminate between soluble HLA-G protein yielded by shedding from membrane-bound HLA-G forms that do not contain the intron 4-encoded epitope and soluble HLA-G5/HLA-G6 produced from intron 4-retaining alternatively spliced mRNAs. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.

Content And Storage

Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Western Blot

Clone

2A12

Conjugate

FITC

Dilution

Flow Cytometry (5 ug/mL) The optimal working dilution should be determined by the end user.

Gene

HLA-G

Gene Symbols

HLA-G

Immunogen

A synthetic peptide (conjugated with OVA) corresponding to C-terminus of human soluble HLA-G5 and HLA-G6.

Regulatory Status

RUO

Gene ID (Entrez)

3135

Target Species

Human

Form

Liquid

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Description

  • HLA-G belongs to the HLA class I heavy chain paralogues
  • This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
  • The heavy chain is anchored in the membrane
  • HLA-G is expressed on fetal derived placental cells
  • The heavy chain is approximately 45kDa and its gene contains 8 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail
  • [provided by RefSeq