NFKBIA, Mouse, Clone: 6A055, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-110-609-Each-of-1 | In Stock | ₹ 70,488.00 |
89-110-609 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,488.00
GST (18%): ₹ 12,687.84
Total Price: ₹ 83,175.84
Antigen
NFKBIA
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Western Blot (0.5-4 ug/mL) Immunoprecipitation (1-4 ug/mL) The optimal working dilution should be determined by the end user.
Gene
NFKBIA
Gene Symbols
NFKBIA
Immunogen
Recombinant protein corresponding to human NFKBIA.
Regulatory Status
RUO
Gene ID (Entrez)
4792
Content And Storage
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
Applications
Immunoprecipitation, Western Blot
Clone
6A055
Description
Mouse monoclonal antibody raised against recombinant NFKBIA.
Formulation
In PBS, pH 7.2 (50% glycerol, 1% BSA, 0.02% thimerosal)
Gene Alias
IKBA/MAD-3/NFKBI
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody detects both phosphorylated and non-phosphorylated forms of NFKBIA.
Form
Liquid
Related Products
Description
- NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex
- The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm
- Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex
- Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM