89-110-770

CDKN1A, Mouse, Clone: DCS-60, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-110-770-Each-of-1 In Stock ₹ 84,728.00

89-110-770 - Each of 1

₹ 84,728.00

In Stock

Quantity

1

Base Price: ₹ 84,728.00

GST (18%): ₹ 15,251.04

Total Price: ₹ 99,979.04

Antigen

CDKN1A

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Western blot (1 to 5 ug /mL) The optimal working dilution should be determined by the end user.

Gene

CDKN1A

Gene Symbols

CDKN1A

Immunogen

Recombinant protein corresponding to full length human CDKN1A .

Regulatory Status

RUO

Gene ID (Entrez)

1026

Form

Liquid

Applications

Immunofluorescence, Immunoprecipitation, Western Blot

Clone

DCS-60

Description

Mouse monoclonal antibody raised against full length recombinant CDKN1A.

Formulation

In PBS (0.08% sodium azide)

Gene Alias

CAP20/CDKN1/CIP1/MDA-6/P21/SDI1/WAF1/p21CIP1

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a

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Description

  • This gene encodes a potent cyclin-dependent kinase inhibitor
  • The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1
  • The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli
  • This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair
  • This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation
  • Two alternatively spliced variants, which encode an identical protein, have been reported
  • [provided by RefSeq