GP1BA, Mouse, Clone: SZ2, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-111-714-Each-of-1 | In Stock | ₹ 1,39,196.00 |
89-111-714 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,39,196.00
GST (18%): ₹ 25,055.28
Total Price: ₹ 1,64,251.28
Antigen
GP1BA
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Flow Cytometry (2ug/5x106platelets/test) The optimal working dilution should be determined by the end user.
Gene
GP1BA
Gene Symbols
GP1BA
Immunogen
Native purified GP1BA from human washed platelets.
Regulatory Status
RUO
Gene ID (Entrez)
2811
Target Species
Human
Form
Lyophilized
Applications
Flow Cytometry, Immunoprecipitation
Clone
SZ2
Description
Mouse monoclonal antibody raised against native GP1BA.
Formulation
Lyophilized from PBS (1mg/mL BSA)
Gene Alias
BSS/CD42B/CD42b-alpha/GP1B/MGC34595
Host Species
Mouse
Quantity
200 μg
Primary or Secondary
Primary
Test Specificity
The molecular weight of the recognized antigen is 160KDa. Reacts with glycoprotein Ib on megakaryocytes and platelets. Inhibits the ristocetin-dependent binding of Von Willebrand factor to platelets and ristocetin induced platelet agglutination. Inhibits platelet aggregation induced by Type I collagen and platelet activating factor (PAF). Immunoprecipitates the components of glycoprotein Ib complex.
Content And Storage
Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
Related Products
Description
- Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds
- The Gp Ib functions as a receptor for von Willebrand factor (VWF)
- The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V
- The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis
- This gene encodes the alpha subunit
- Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease
- [provided by RefSeq