APAF1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-116-328-Each-of-1 | In Stock | ₹ 76,718.00 |
89-116-328 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 76,718.00
GST (18%): ₹ 13,809.24
Total Price: ₹ 90,527.24
Antigen
APAF1
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against synthetic peptide of APAF1.
Formulation
In PBS (0.02% sodium azide)
Gene Accession No.
AAC51678
Gene Symbols
APAF1
Immunogen
A synthetic peptide corresponding to N-terminus of human APAF1.
Regulatory Status
RUO
Gene ID (Entrez)
317
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunohistochemistry (PFA fixed), Western Blot
Conjugate
Unconjugated
Dilution
Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Gene
APAF1
Gene Alias
CED4/DKFZp781B1145
Host Species
Rabbit
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
The sequences of the immunogenic peptide are identical between human and mouse.
Content And Storage
Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
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Description
- This gene encodes a cytoplasmic protein that initiates apoptosis
- This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC)
- Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome
- The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form
- Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis
- Alternative splicing results in several transcript variants encoding different isoforms
- [provided by RefSeq