89-130-711

BRAF (phospho T599), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-130-711-Each-of-1 In Stock ₹ 57,138.00

89-130-711 - Each of 1

₹ 57,138.00

In Stock

Quantity

1

Base Price: ₹ 57,138.00

GST (18%): ₹ 10,284.84

Total Price: ₹ 67,422.84

Antigen

BRAF

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BRAF.

Formulation

In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.

P15056

Gene Symbols

BRAF

Immunogen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T599 of human BRAF.

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

BRAF (phospho T599) polyclonal antibody detects endogenous levels of human BRAF only when phosphorylated at threonine 599.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

Immunohistochemistry (PFA fixed)

Conjugate

Unconjugated

Dilution

Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.

Gene

BRAF

Gene Alias

B-RAF1/BRAF1/FLJ95109/MGC126806/MGC138284/RAFB1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

673

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases
  • This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion
  • Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance
  • Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, nonsmall cell lung carcinoma, and adenocarcinoma of lung
  • A pseudogene, which is located on chromosome X, has been identified for this gene
  • [provided by RefSeq