POMC, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-132-678-Each-of-1 | In Stock | ₹ 70,399.00 |
89-132-678 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
POMC
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:2000) Western blot (1-3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL) The optimal working dilution should be determined by the end user.
Gene
POMC
Gene Symbols
POMC
Immunogen
A synthetic peptide corresponding to C-terminus of human POMC.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
Both transcript variants encode the same protein. In Western blot, this product appears to react with the full length precursor protein only.
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Immunohistochemistry (PFA fixed)
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of POMC.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Alias
ACTH/CLIP/LPH/MSH/NPP/POC
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
5443
Target Species
Human, Mouse
Form
Liquid
Related Products
Description
- This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases
- There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions
- The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products
- In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation
- These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides
- Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation
- Alternatively spliced transcript variants encoding the same protein have been described
- [provided by RefSeq Sequence: C-NAIIKNAYKKGE