ALPL Mouse anti-Human, Clone: 2F4, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-933-560-Each-of-1 | In Stock | ₹ 85,173.00 |
89-933-560 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 85,173.00
GST (18%): ₹ 15,331.14
Total Price: ₹ 1,00,504.14
Antigen
ALPL
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
Gene Alias
AP-TNAP/FLJ40094/FLJ93059/HOPS/MGC161443/MGC167935/TNAP/TNSALP
Host Species
Mouse
Purification Method
Protein G purification
Regulatory Status
RUO
Gene ID (Entrez)
249
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
Clone
2F4
Description
Mouse monoclonal antibody raised against partial recombinant human ALPL.
Formulation
In PBS (0.05% protein stabilizer, 0.05% sodium azide).
Gene Symbols
ALPL
Immunogen
Recombinant protein corresponding to amino acids 18-502 of human ALPL.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific)
- The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1
- The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme
- The exact physiological function of the alkaline phosphatases is not known
- A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development
- This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects
- The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms
- Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene
- [provided by RefSeq]