FGFR4 Mouse anti-Human, Clone: 53CT32.19.3, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-934-143-Each-of-1 | In Stock | ₹ 85,173.00 |
89-934-143 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 85,173.00
GST (18%): ₹ 15,331.14
Total Price: ₹ 1,00,504.14
Antigen
FGFR4
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1:2000) The optimal working dilution should be determined by the end user.
Gene Alias
CD334/JTK2/MGC20292/TKF
Host Species
Mouse
Purification Method
Protein G purification
Regulatory Status
RUO
Gene ID (Entrez)
2264
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Applications
Immunohistochemistry (PFA fixed), Western Blot
Clone
53CT32.19.3
Description
Mouse monoclonal antibody raised against human FGFR4.
Formulation
In PBS (0.09% sodium azide).
Gene Symbols
FGFR4
Immunogen
Recombinant protein corresponding to human FGFR4.
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution
- FGFR family members differ from one another in their ligand affinities and tissue distribution
- A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain
- The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation
- The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20
- Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3
- This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis
- [provided by RefSeq]