FGFR1 Mouse anti-Human, Clone: M2F12, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-934-141-Each-of-1 | In Stock | ₹ 82,503.00 |
89-934-141 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 82,503.00
GST (18%): ₹ 14,850.54
Total Price: ₹ 97,353.54
Antigen
FGFR1
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Immunoprecipitation Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias
BFGFR/CD331/CEK/FGFBR/FLG/FLJ99988/FLT2/HBGFR/KAL2/N-SAM
Host Species
Mouse
Purification Method
Protein G purification
Regulatory Status
RUO
Gene ID (Entrez)
2260
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a
Applications
Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone
M2F12
Description
Mouse monoclonal antibody raised against human FGFR1.
Formulation
In PBS, pH 7.4.
Gene Symbols
FGFR1
Immunogen
Recombinant protein corresponding to N-terminus of human FGFR1.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution
- FGFR family members differ from one another in their ligand affinities and tissue distribution
- A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain
- The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation
- This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction
- Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2
- Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome
- Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized
- [provided by RefSeq]