ATM Mouse anti-Human, Clone: 3E8, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-933-596-Each-of-1 | In Stock | ₹ 85,173.00 |
89-933-596 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 85,173.00
GST (18%): ₹ 15,331.14
Total Price: ₹ 1,00,504.14
Antigen
ATM
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.
Gene Alias
AT1/ATA/ATC/ATD/ATDC/ATE/DKFZp781A0353/MGC74674/TEL1/TELO1
Host Species
Mouse
Purification Method
Protein G purification
Regulatory Status
RUO
Gene ID (Entrez)
472
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
Applications
Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone
3E8
Description
Mouse monoclonal antibody raised against partial recombinant human ATM.
Formulation
In PBS, pH 7.4.
Gene Symbols
ATM
Immunogen
Recombinant protein corresponding to amino acids 980-1512 of human ATM.
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- The protein encoded by this gene belongs to the PI3/PI4-kinase family
- This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1
- This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability
- Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder
- Two transcript variants encoding different isoforms have been found for this gene
- [provided by RefSeq]