ABC926MI
MilliporeSigma™ Rabbit anti-TRIM11, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABC926MI-Each-of-1 | In Stock | ₹ 43,318.08 |
ABC926MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,318.08
GST (18%): ₹ 7,797.254
Total Price: ₹ 51,115.334
Antigen
TRIM11
Classification
Polyclonal
Gene Accession No.
Q96F44
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Applications
Immunohistochemistry (Paraffin), Western Blot
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
TRIM11; RNF92
Immunogen
KLH-conjugated linear peptide corresponding to human TRIM11.
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_660215
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
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Description
- Specifically detects TRIM11 in Human, Mouse samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting E3 ubiquitin-protein ligase TRIM11 (UniProt Q96F44; also known as Protein BIA1, RING finger protein 92, Tripartite motif-containing 11, Tripartite motif-containing protein 11) is encoded by the TRIM11 (also known as BIA1, RNF92) gene (Gene ID 81559) in human
- TRIM11 belongs to a family of more than 70 TRIM/RBCC proteins characterized by their shared tripartite motif structure, also known as the RBCC (RING finger, B-box, and coiled-coil) domain
- The B-box and coiled coil regions are believed to participate in protein-protein interactions and formation of macromolecular complexes
- TRIM proteins are involved in diverse cellular processes, including cell proliferation, differentiation, oncogenesis, and apoptosis
- The presence of a RING domain suggests that TRIM proteins function as E3 ubiquitin ligases
- The neuroprotective peptide humanin, activator-recruited cofactor (ARC) 105-kDa component (ARC105), the transcription factors Pax6 and PHOX2B are all known subrates targeted by TRIM11-mediated degradation through the ubiquitin-proteasome system
- In addition, TRIM11 is also reported to interfere with the early steps of HIV-1 replication in host cells in a RING domain-dependent manner.