ABE860MI

MilliporeSigma™ Rabbit anti-TRAF3, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABE860MI-Each-of-1 In Stock ₹ 44,393.20

ABE860MI - Each of 1

₹ 44,393.20

In Stock

Quantity

1

Base Price: ₹ 44,393.20

GST (18%): ₹ 7,990.776

Total Price: ₹ 52,383.976

Antigen

TRAF3

Classification

Polyclonal

Gene Accession No.

Q13114

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Applications

Immunocytochemistry, Western Blot

Formulation

Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.

Gene Symbols

TRAF3; CAP1; CRAF1

Immunogen

TRAF3 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TRAF3.

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Target Species

Human

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Description

  • Specifically detects TRAF3 in Human samples, and it is validated for Immunocytochemistry, Western Blotting TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1)
  • TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response
  • It modulates signaling pathways leading to the production of cytokines and interferon
  • As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins
  • Moreover, TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5.