ABT543MI
MilliporeSigma™ Rabbit anti-Claudin-4, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABT543MI-Each-of-1 | In Stock | ₹ 42,968.31 |
ABT543MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,968.31
GST (18%): ₹ 7,734.296
Total Price: ₹ 50,702.606
Antigen
Claudin-4
Classification
Polyclonal
Gene Accession No.
O14493
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Applications
Immunocytochemistry, Western Blot
Formulation
Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
Gene Symbols
CLDN4; CPER; CPETR1; WBSCR8
Immunogen
Claudin-4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human Claudin-4.
Quantity
100 μg
Research Discipline
Cell Structure
Target Species
Human
Related Products
Description
- Specifically detects Claudin-4 in Human samples, and it is validated for Immunocytochemistry, Western Blotting Claudin 4, also known as Clostridium perfringens enterotoxin receptor, or CPE-R, or CPE-receptor or Williams-Beuren syndrome chromosomal region 8 protein, and encoded by the gene CLDN4/CPER/CPETR1/WBSCR8, plays a critical role in tight junction specific obliteration of intercellular space
- Claudin 4 directly interacts with several important tight junction associated proteins including ZO-1,2,3 and EPHA2 proteins, and through these interactions, Claudin 4 regulates tight junction formation
- Claudin 4 is localized to cell junctions and membranes at tight junctions
- Claudin 4 is expressed in most tissues particularly in intestine, liver, and pancreas
- Defects in Claudin 4 may be associated with Williams Beuren syndrome genetic deletion syndrome
- Claudin 4 is also over expressed in many cancers and thus is a target of anti-cancer research using C
- perfringens enterotoxin.