MilliporeSigma™ Prodynorphin/Leumorphin (dynorphin B29) , Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABN1640MI-Each-of-1 | In Stock | ₹ 40,292.08 |
ABN1640MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,292.08
GST (18%): ₹ 7,252.574
Total Price: ₹ 47,544.654
Antigen
Prodynorphin/Leumorphin (dynorphin B29)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pdyn
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antiserum recognizes preproenkephalin-B (a.a. 1-248 of rat sequence), proenkephalin-B (a.a. 22-248 of rat sequence), and leumorphin/dynorphin B-29 (a.a. 221-248 of rat sequence), but not other peptides derived from Proenkephalin-B.
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.
P06300
Immunogen
Linear peptide corresponding to rat leumorphin (dynorphin B-29) C-terminal half sequence.
Quantity
50 μL
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_062247
Target Species
Human
Form
Serum
Related Products
Description
- Proenkephalin-B (UniProt P06300; also known as Beta-neoendorphin-dynorphin, Preprodynorphin) is encoded by the Pdyn gene (Gene ID 29190) in rat species
- Proenkephalin B is an opioid polypeptide hormone involved with chemical signal transduction and cell communication
- Prodynorphin is a basic building-block of endorphins, the chemical messengers in the brain that appear most heavily involved in the anticipation and experience of pain and the formation of deep emotional bonds critical in learning and memory
- Prodynorphin is produced with a signal peptide (a.a
- 1-21) and a propeptide (a.a
- 22-163) sequence
- Following the removal of the signal and propeptide sequences, the protein is further processed by proeolytic cleavages to form Alpha-neoendorphin (a.a
- 166-175), Beta-neoendorphin (a.a
- 166-174), Big dynorphin (a.a
- 202-233; Big Dyn), Dynorphin A(1-17) (a.a
- 202-218; Dyn-A17; Dynorphin A); Dynorphin A(1-13) (a.a
- 202-214), Dynorphin A(1-8) (a.a
- 202-209), Leu-enkephalin (a.a
- 202-206 and 221-225), Leumorphin (Dynorphin B-29; a.a
- 221-248), and Rimorphin (a.a
- 221-233; Dynorphin B; Dyn-B; Dynorphin B(1-13)).