SRC Monoclonal Antibody (184Q20), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AHO1152-Each-of-1 | In Stock | ₹ 44,500.00 |
AHO1152 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,500.00
GST (18%): ₹ 8,010.00
Total Price: ₹ 52,510.00
Antigen
SRC
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.
P05480, P12931, Q9WUD9
Gene Symbols
SRC
Immunogen
Recombinant human c-Src expressed in E. coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
184Q20
Conjugate
Unconjugated
Gene
SRC
Gene Alias
ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma viral oncogene; wu:fc54g04; XELAEV_18046582mg; xsrc
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20779, 6714, 83805
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth
- SRC is involved in the regulation of growth and differentiation of eukaryotic cells
- SRC associates with the cytoplasmic region of various cell surface receptors to facilitate signal transduction, and is also involved in cytoskeletal organization, cell cycle regulation, and apoptosis
- In humans, the gene encoding SRC is present on chromosome 20
- Activity of SRC is regulated by two tyrosine residues (Tyr 416 and Tyr527), and phosphorylation of these two sites have opposing effects
- Phosphorylation of Tyr416 in the activation loop of the kinase domain upregulates enzyme activity while the phosphorylation of Tyr527 decreases enzyme activity
- Mutations in the SRC gene could be involved in the malignant progression of colon cancer
- Two transcript variants encoding the same SRC protein have been found thus far.