SPRED1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA584518-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA584518 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
SPRED1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SPRED1
Gene Alias
5730461F13Rik; AL024345; AW047647; hSpred1; NFLS; PPP1R147; protein phosphatase 1, regulatory subunit 147; SPRED1; spred-1; sprouty protein with EVH-1 domain 1, related sequence; sprouty related EVH1 domain containing 1; sprouty related, EVH1 domain containing 1; sprouty-related protein 1 with EVH-1 domain; sprouty-related, EVH1 domain containing 1; sprouty-related, EVH1 domain-containing protein 1; suppressor of Ras/MAPK activation
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
161742
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q7Z699
Gene Symbols
SPRED1
Immunogen
Recombinant protein corresponding to Human SPRED1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: GGSGLSSVTV FKVPHQEENG CADFFIRGER LRDKMVVLEC MLKKDLIYNK VTP The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes; it is inhibited by Spred1, a member of the Sprouty family of proteins
- Spred1 acts by suppressing the phosphorylation and activation of Raf
- The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis
- Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC
- Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).