alpha Internexin Monoclonal Antibody (2E3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AMSA6726-Each-of-1 | In Stock | ₹ 47,481.50 |
AMSA6726 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
alpha Internexin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.
P23565, P46660, Q08DH7, Q16352
Gene Symbols
INA
Immunogen
Purified recombinant rat a-internexin.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
2E3
Conjugate
Unconjugated
Gene
INA
Gene Alias
66 kDa neurofilament protein; Alpha-internexin; alpha-Inx; AV028420; FLJ18662; FLJ57501; Ina; Inexa; internexin neuronal intermediate filament protein alpha; internexin neuronal intermediate filament protein, alpha; internexin, alpha; Intlaa; LOW QUALITY PROTEIN: alpha-internexin; MGC12702; NEF5; Neuro; Neurofilament 5; neurofilament 5 (66kD); Neurofilament 66; neurofilament-66; neurofilament-66, tax-binding protein; Nf66; NF-66; TXBP-1
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100153400, 226180, 24503, 532236, 9118
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- The epitope recognized by the 2E3 clone is in the C-terminal non-helical extension of the protein and is unusually resistant to aldehyde fixation, so this antibody is ideal for studies of formalin-fixed paraffin-embedded histological sections
- alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development
- It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization
- Many classes of mature neurons contain a-internexin in addition to NF-L, NF-M and NF-H
- In some mature neurons a-internexin is the only neurofilament subunit expressed
- Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture
- In addition the very early developmental expression of a-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage
- The use of antibodies to this protein in the study of brain tumors has not been examined to date, but is likely to be of interest.