AMSA6752

alpha Internexin Monoclonal Antibody (1D2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 AMSA6752-Each-of-1 In Stock ₹ 47,481.50

AMSA6752 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

alpha Internexin

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

tissue culture supernatant diluted in PBS with 50% glycerol and no preservative

Gene Accession No.

P23565, P46660, Q16352

Gene Symbols

INA

Immunogen

Raised against purified recombinant rat alpha-internexin expressed in and purified from E. coli.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Feline, Human, Mammalia, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Free Floating), Immunohistochemistry (Paraffin), Western Blot

Clone

1D2

Conjugate

Unconjugated

Gene

INA

Gene Alias

66 kDa neurofilament protein; Alpha-internexin; alpha-Inx; AV028420; FLJ18662; FLJ57501; Ina; Inexa; internexin neuronal intermediate filament protein alpha; internexin neuronal intermediate filament protein, alpha; internexin, alpha; Intlaa; LOW QUALITY PROTEIN: alpha-internexin; MGC12702; NEF5; Neuro; Neurofilament 5; neurofilament 5 (66kD); Neurofilament 66; neurofilament-66; neurofilament-66, tax-binding protein; Nf66; NF-66; TXBP-1

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

101085925, 226180, 24503, 9118

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development
  • It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization
  • Many classes of mature neurons contain a-internexin in addition to NF-L, NF-M and NF-H
  • In some mature neurons a-internexin is the only neurofilament subunit expressed
  • Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture
  • In addition the very early developmental expression of a-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage
  • The use of antibodies to this protein in the study of brain tumors has not been examined to date, but is likely to be of interest.