APPA6759

Vimentin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APPA6759-Each-of-1 In Stock ₹ 56,782.00

APPA6759 - Each of 1

₹ 56,782.00

In Stock

Quantity

1

Base Price: ₹ 56,782.00

GST (18%): ₹ 10,220.76

Total Price: ₹ 67,002.76

Antigen

Vimentin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Vim

Gene Alias

cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus

Host Species

Chicken

Purification Method

IgY fraction

Regulatory Status

RUO

Gene ID (Entrez)

100056088, 100522394, 22352, 280955, 420519, 477991, 7431, 81818

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

16.6 mg/mL

Formulation

PBS with 5mM sodium azide

Gene Accession No.

P02543, P08670, P09654, P20152, P31000, P48616

Gene Symbols

Vim

Immunogen

The immunogen used to generate our antibody was recombinant vimentin purified from E. coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Canine, Chicken, Equine, Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgY

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Description

  • Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin
  • It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane
  • Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development
  • During the development process, vimentin is exchanged for new, tissue-specific IFPs
  • Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets
  • Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event
  • This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.