53BP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APPA6566-Each-of-1 | In Stock | ₹ 48,015.50 |
APPA6566 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,015.50
GST (18%): ₹ 8,642.79
Total Price: ₹ 56,658.29
Antigen
53BP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TP53BP1
Gene Alias
53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27223, 296099, 478274, 509111, 7158
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P70399, Q12888
Gene Symbols
TP53BP1, Trp53bp1
Immunogen
Region between residues 1925 and the C-terminus (residue 1972) of human 53BP1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bat, Bovine, Canine, Human, Mouse, Rat, Rodent
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Human samples have been tested in Western Blot and ICC/IF, and mouse samples have been tested in ICC/IF only
- Suggested positive control: U205, 293T, and MO59K cell lysates and MEF lysates
- 53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase
- Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks
- 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.