CYR61 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APPA6579-Each-of-1 | In Stock | ₹ 49,706.50 |
APPA6579 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,706.50
GST (18%): ₹ 8,947.17
Total Price: ₹ 58,653.67
Antigen
CYR61
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CCN1
Gene Alias
3CH61; AI325051; CCN family member 1; CCN1; cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61; Protein GIG1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100339657, 16007, 3491
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Neutralization, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O00622, P18406
Gene Symbols
CCN1
Immunogen
A synthetic peptide made to the human CYR61 protein sequence (between residues 150-250).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rabbit
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with rat and mouse based on 88% sequence homology
- Suggested positive control: antigen standard for CYR61 (transient overexpression lysate), MDA-MB-231 breast cancer cell lysate
- CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue
- CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12
- As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells
- Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation
- CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.