BDB550495
CD91 Mouse anti-Human, Unlabeled, Clone: A2MR-A2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB550495-Each-of-1 | In Stock | ₹ 16,198.00 |
BDB550495 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,198.00
GST (18%): ₹ 2,915.64
Total Price: ₹ 19,113.64
Antigen
CD91
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Alpha-2-macroglobulin receptor; α2MR; LRP-1; LDL Receptor-Related Protein-1
Host Species
Mouse
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
A2MR-A2
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Reacts with a 600kDa, type I membrane single protein, also known as the α2 Macroglobulin (α2M) receptor/low density lipoprotein (LDL) receptor
- The single chain receptor undergoes cleavage, shortly after synthesis, into the 85kDa transmembrane β chain that non-covalently binds to the extracellular 500-515kDa a chain
- It has a broad cellular distribution, but in the hematopoietic system it is expressed on monocyte lineage cells
- The α2M/LDL receptor mediates endocytosis of a variety of ligands including α2M-proteinase complexes, plasminogen activators in complex with plasminogen activator inhibitor, Pseudomonas Exotoxin A
- Ligand binding to α2M/LDL receptor is followed by rapid transport of the ligand to lysosomes for degradation
- Host Species: Mouse Clone: A2MR-α2 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry