BDB551458
CD63 Mouse anti-Rat, Unlabeled, Clone: AD1, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB551458-Each-of-1 | In Stock | ₹ 14,062.00 |
BDB551458 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,062.00
GST (18%): ₹ 2,531.16
Total Price: ₹ 16,593.16
Antigen
CD63
Classification
Monoclonal
Concentration
0.5mg/mL
Description
ME491
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
AD1
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Rat basophilic leukemia cell line
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Rat
Isotype
IgG1 κ
Related Products
Description
- The AD1 antibody reacts with a 50-60-kDa protein that is a homolog (87%) ofhuman CD63 (melanomaassociated antigen ME491)
- CD63, a highly glycosylated type-III lysosomal glycoprotein, is a member of the tetraspan transmembrane 4 superfamily (TM4SF) that also includes CD9, CD37, and CD53
- In the rat, CD63 is expressed on mast cells and platelets
- CD63 is also found on rat embryonic fibroblasts and hepatic cell, along with cultured cell lines of diverse origin (eg, liver, lung, and heart)
- Expression is upregulated with culture
- CD63 is expressed in close proximity to the FcεRI on rat mast cells and has been shown to partially inhibit IgE-mediated histamine release
- The function of CD63 has not been fully characterized.