BDB551469
IgE Receptor Mouse anti-Rat, Unlabeled, Clone: BC4, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB551469-Each-of-1 | In Stock | ₹ 12,638.00 |
BDB551469 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,638.00
GST (18%): ₹ 2,274.84
Total Price: ₹ 14,912.84
Antigen
IgE Receptor
Classification
Monoclonal
Concentration
0.5mg/mL
Description
FcεRI
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
BC4
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Rat basophilic leukemia cell line
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Rat
Isotype
IgG1 κ
Related Products
Description
- The BC4 antibody reacts with the high-affinity IgE Fc receptor (FcεRI) expressed in rat mast cells, basophils, and non-B non-T cells
- The rat FcεRI is expressed as a tetrameric molecule consisting of one α chain, one β chain, and two identical γ chains
- The BC4 antibody has been reported to detect all three chains of the FcεRI by immunoprecipitation
- In the rat model, the β chain (FcRβ) is required for cell-surface expression of the complete FcεRI
- This differs from the human FcεRI, which can be expressed in trimer (αγ2) or tetramer forms (βγ2)
- Furthermore, the FcRβ has been characterized as a potent signaling molecule capable of substantially amplifying Fc-mediated cellular responses
- The FcεRI functions to mediate cellular degranulation and the release of histamine, leukotrienes, and various cytokines and chemokines
- The structure, expression, function, and signaling mechanisms of the FcεRI have been reviewed
- Host Species: Mouse Clone: BC4 Isotype: IgG1 κ Species Reactivity: Rat Immunogen: Rat basophilic leukemia cell line Flow Cytometry, Immunoprecipitation