BDB554951
CD61 Mouse anti-Rat, Unlabeled, Clone: F11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB554951-Each-of-1 | In Stock | ₹ 27,590.00 |
BDB554951 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,590.00
GST (18%): ₹ 4,966.20
Total Price: ₹ 32,556.20
Antigen
CD61
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Integrin β3 chain
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
F11
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Rat bone cell suspensions
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Rat
Isotype
IgG1 κ
Related Products
Description
- The F11 antibody reacts with the integrin β3 chain (CD61), which associates with the integrin αv chain (CD51), to form the vitronectin receptor found on endothelial cells, myeloid cells, and osteoclasts, and with the αIIb chain (CD41) on platelets and megakaryocytes
- Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor
- F11 mAb has been reported to block the in vitro attachment of osteoclasts to several ligands
- Weak reactivity with human osteoclasts, megakaryocytes, and platelets has also been observed
- Other reported applications include immunoprecipitation, in vitro blocking, and immunohistochemical staining (IHC) of acetone-fixed frozen and zinc-fixed paraffin-embedded sections
- IHC of formalin-fixed paraffin-embedded sections is not recommended.