BDB551968

CD184 Rat anti-Mouse, Biotin, Clone: 2B11/CXCR4, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB551968-Each-of-1 In Stock ₹ 26,121.50

BDB551968 - Each of 1

₹ 26,121.50

In Stock

Quantity

1

Base Price: ₹ 26,121.50

GST (18%): ₹ 4,701.87

Total Price: ₹ 30,823.37

Antigen

CD184

Classification

Monoclonal

Concentration

0.5mg/mL

Description

CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

2B11/CXCR4

Conjugate

Biotin

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

GST-NCXCR4 fusion protein

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b κ

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Description

  • The 2B11/CXCR4 monoclonal antibody specifically binds to mouse CD184 which is also known as the CXC chemokine receptor, CXCR4
  • CXCR4 (previously known as Fusin and LESTR), is a seven-transmembrane, G-protein-coupled receptor
  • It is the specific receptor for the CXC chemokine, SDF-1/CXCL12
  • Mouse CXCR4 shows 91% homology at the amino acid level with human CXCR4
  • CXCR4 is widely expressed by hematopoietic and non-hematopoietic cell types including neutrophils, monocytes, T cells, B cells, CD34-positive progenitor cells, endothelial cells, neurons and astrocytes
  • Human CXCR4 is used by T-tropic HIV-1 as a co-receptor for viral entry
  • The mouse Cxcr4 gene has been mapped to chromosome 1.