BDB552422
IL-18 Receptor β Rat anti-Mouse, NA/LE, Unlabeled, Clone: TC30-28E3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552422-Each-of-1 | In Stock | ₹ 37,736.00 |
BDB552422 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,736.00
GST (18%): ₹ 6,792.48
Total Price: ₹ 44,528.48
Antigen
IL-18 Receptor β
Classification
Monoclonal
Concentration
1.0mg/mL
Description
IL-1RAcPL, IL-R7
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Neutralization
Clone
TC30-28E3
Conjugate
Unconjugated
Formulation
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
Mouse sIL-1R7 fusion protein
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a λ
Related Products
Description
- The TC30-28E3 antibody specifically binds to the β subunit of the mouse Interleukin-18 Receptor complex (IL-18Rβ)
- The mouse IL-18R complex is expressed by T cells stimulated with IL-12 alone or cultured with antigen and IL-12 to induce Th1 cells
- IL-18R is constitutively expressed by NK cells
- Resting mouse T cells and Th2 cells do not express detectable levels of IL-18R
- The mouse IL-18R complex consists of the IL-18α chain, also known as IL-1 Receptor related protein 1 (IL-1Rrp1 or IL-R5) and the IL-18Rβ chain also known as IL-1R accessory protein-like (IL-1RAcPL or IL-R7)
- The cell surface IL-18Rα chain binds IL-18 with low affinity
- However its interaction with the IL-18Rβ chain confers high affinity binding for the ligand
- The IL-18Rβ chain is not involved in ligand binding but is responsible for the transduction of biological signals
- The immunogen used to generate the TC30-28E3 hybridoma was sIL-1R7 fusion protein
- Host Species: Rat Clone: TC30-28E3 Isotype: IgG2a κ Species Reactivity: Mouse Immunogen: Mouse sIL-1R7 fusion protein Neutralization