BDB553296
CD28 Hamster anti-Mouse, Biotin, Clone: 37.51, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB553296-Each-of-1 | In Stock | ₹ 30,972.00 |
BDB553296 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,972.00
GST (18%): ₹ 5,574.96
Total Price: ₹ 36,546.96
Antigen
CD28
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
Mouse EL-4 (T-cell lymphoma) Cells
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2 λ1
Applications
Flow Cytometry
Clone
37.51
Conjugate
Biotin
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 37.51 antibody reacts with CD28, which is expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T cells, and at even lower density on NK cells
- The expression of CD28, in splenocytes and thymocytes,has been reported to increase after activation
- CD28 transcripts are found in mast cells, and cell-surface expression of CD28 is induced upon maturation or activation of mast cells
- It has been reported that CD28 is not expressed on some populations of intraepithelial T lymphocytes
- CD28 is a costimulatory receptor; its ligands include CD80 (B7-1) and CD86 (B7-2)
- The 37.51 mAb augments proliferation and cytokine production by activated T and NK cells and can provide a costimulatory signal for CTL induction
- There is considerable evidence that CD28 is a costimulatory receptor involved in many, but not all, T cell-dependent immune responses
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.